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Medications
St. John’s Wort and SSRIs: The Dangerous Risk of Serotonin Syndrome
- Gareth Wycliffe
- May 9, 2026
Mixing St. John's Wort with SSRIs like sertraline or fluoxetine can cause serotonin syndrome, a life-threatening condition. Learn why this natural supplement interacts dangerously with prescription antidepressants.